3,3′,4,4′,5-Pentachlorobiphenyl Inhibits Drug Efflux Through P-Glycoprotein in KB-3 Cells Expressing Mutant Human P-Glycoprotein
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منابع مشابه
3,3′,4,4′,5-Pentachlorobiphenyl Inhibits Drug Efflux Through P-Glycoprotein in KB-3 Cells Expressing Mutant Human P-Glycoprotein
The effects on the drug efflux of $3,3',4,4',5$ -pentachlorobiphenyl (PCB-126), the most toxic of all coplanar polychlorinated biphenyls (Co-PCBs), were examined in KB-3 cells expressing human wild-type and mutant P-glycoprotein in which the 61st amino acid was substituted for serine or phenylalanine ( ${\text{KB3 - Phe}};{61} $ ). In the cells expressing P-glycoproteins, accumulations of vinbl...
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ژورنال
عنوان ژورنال: Journal of Biomedicine and Biotechnology
سال: 2004
ISSN: 1110-7243,1110-7251
DOI: 10.1155/s1110724304308028